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You can switch to retatrutide after approval for the roughly 6-percentage-point advantage it offers over tirzepatide in its cleanest trials

GLP-1 receptor agonists are a class of FDA-approved medications that mimic this hormone, producing three powerful effects: Appetite suppression signals your brain that youre full sooner and for longer Slowed gastric emptying food moves through your stomach more slowly, reducing hunger spikes Blood sugar regulation stimulates insulin release in response to meals, supporting metabolic health Originally developed for type 2 diabetes management, GLP-1 medications have since been FDA-approved specifically for chronic weight management in adults with obesity or overweight and related health conditions

Your intake also screens for gastroparesis or another condition that slows stomach emptying, a current or past eating disorder, diabetic retinopathy, use of insulin or a sulfonylurea, and any surgery or procedure requiring anesthesia in the next eight weeks

Common side effects of weight loss medications Many people who experience the most common side effects from weight loss medications say they resolve after their bodies adjust to the new medications, while others have side effects that persist

Ozempic is approved only for type 2 diabetes indications